Most cerebellar tumor patients experience classical somatic symptoms such as headaches, nausea and vomiting before surgery. They can also be affected cognitively and emotionally and have problems with language and speech. Ataxia and fine and gross motor problems are common, but patients rarely present with serious neurological signs[2, 3, 4, 5].
The range of symptoms that children with post-operative pediatric CMS can experience post-operatively is wide, and covers all aspects of the syndrome (linguistic, neuropsychological and neurological/motor problems) [2, 3, 4, 6, 7]. The onset of mutism and neuropsychological symptoms is usually accompanied by new/worsening neurological signs (ataxia, paresis, oculomotor dysfunction, reduced facial expression and incontinence) and marked affective/behavioral abnormalities .
Table 1 describes common pre- and post-operative symptoms in children with posterior fossa tumors, based on the old PFS definition (see definitions). The symptomatic spectrume corresponds to the new definition of post-operative pediatric CMS.
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3. Catsman-Berrevoets CE, Aarsen FK (2010) The spectrum of neurobehavioural deficits in the Posterior Fossa Syndrome in children after cerebellar tumour surgery. Cortex 46: 933-946
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